National Institutes of Health Clinical Center (CC) NIH

Regulated TrialsResults on time (%)Results late (%)Results unreported (%)
25222 % ( 55 )
71 % ( 180 )
8 % ( 21 )
Study Title
Start Date
Completion Date
Results Submitted
Tolebrutinib, a Brain-penetrant Bruton s Tyrosine Kinase Inhibitor, for the Modulation of Chronically Inflamed White Matter Lesions in Multiple Sclerosis2021-04-152023-06-15
A Trial of the Safety and Immunogenicity of the COVID-19 Vaccine (mRNA-1273) in Participants With Hematologic Malignancies and Various Regimens of Immunosuppression, and in Participants With Solid Tumors on PD1/PDL1 Inhibitor Therapy2021-04-282023-05-25
Intraperitoneal and Intravenous Paclitaxel Chemotherapy With Oral Capecitabine for Gastric Adenocarcinoma With Peritoneal Carcinomatosis2020-06-092023-02-252023-10-26
Systems Analyses of the Immune Response to the Seasonal Influenza Vaccine2019-10-022023-01-312023-10-03
Radiation Therapy Plus Temozolomide and Pembrolizumab With and Without HSPPC-96 in Newly Diagnosed Glioblastoma (GBM)2017-09-212022-12-202023-12-14
Study of Human Non-Shivering Thermogenesis and Basal Metabolic Rate2014-02-072022-12-17
Randomized Phase II Trial of Rituximab With Either Pentostatin or Bendamustine for Multiply Relapsed or Refractory Hairy Cell Leukemia2010-07-012022-12-152023-10-26
Sodium Thiosulfate for Treatment of Calcinosis Associated With Juvenile and Adult Dermatomyositis2017-10-052022-11-042023-09-29
Nivolumab (Anti-PD1), Tadalafil and Oral Vancomycin in People With Refractory Primary Hepatocellular Carcinoma or Liver Dominant Metastatic Cancer From Colorectal or Pancreatic Cancers2019-06-052022-10-312023-05-24
Mepolizumab in Episodic Angioedema With Eosinophilia2021-01-142022-10-312023-09-28
Phase II Trial of Combination Immunotherapy in Subjects With Advanced Small Bowel and Colorectal Cancers2020-09-222022-10-252023-10-11
Pembrolizumab in Relapsed and Refractory Gray-Zone Lymphoma (GZL), Primary Central Nervous System Lymphoma (PCNSL), and Other Extranodal Diffuse Large B-cell Lymphomas2018-02-152022-10-222023-09-08
Enzalutamide With or Without Vaccine Therapy for Advanced Prostate Cancer2013-08-122022-09-282023-07-21
Evaluation of Oral Minocycline in the Treatment of Geographic Atrophy Associated With Age-Related Macular Degeneration2016-12-142022-09-282023-08-31
Protein Phosphatase 2A Inhibitor, in Recurrent Glioblastoma2019-01-092022-08-152023-08-11
Ibrutinib, Fludarabine, and Pembrolizumab in High-Risk or Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma2017-09-222022-07-182023-03-23
Docetaxel and PROSTVAC for Metastatic Castration-Sensitive Prostate Cancer2016-01-192022-07-012023-05-16
The Safety of Administering a Second Dose of a COVID-19 mRNA Vaccine in Individuals Who Experienced a Systemic Allergic Reaction to an Initial Dose2021-09-082022-06-172023-06-16
Fixed Dose Flavonoid Isoquercetin on Thrombo-Inflammatory Biomarkers in Subjects With Stable Sickle Cell Disease2020-11-022022-06-132023-06-02
Perioperative MVT-5873, a Fully Human Monoclonal Antibody Against a CA 19-9 Epitope, for Operable CA 19-9 Producing Pancreatic Cancers, Cholangiocarcinomas, and Metastatic Colorectal Cancers2019-11-132022-05-272023-02-27
Local Ablative Therapy for Treatment of Oligoprogressive, EGFR-Mutated, Non-Small Cell Lung Cancer After Treatment With Osimertinib2016-04-132022-05-252023-05-10
Combination of Trametinib (MEK Inhibitor) and Hydroxychloroquine (HCQ) (Autophagy Inhibitor) in Patients With KRAS Mutation Refractory Bile Tract Carcinoma (BTC).2022-02-152022-05-112023-05-12
Xenodiagnosis After Antibiotic Treatment for Lyme Disease2015-07-242022-05-042024-04-29
A Phase II Study of Bevacizumab and Erlotinib in Subjects With Advanced Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) or Sporadic Papillary Renal Cell Cancer2010-05-062022-04-122023-04-12
VB-111 in Combination With Nivolumab in People With Metastatic Colorectal Cancer (mCRC)2020-08-092022-04-122023-03-27
Hepatitis B Immune Globulin (HBIg) to Restore Immune Control in People With Chronic Hepatitis B2019-02-132022-03-29
Long-Term TARP Vaccination Using a Multi-Epitope TARP Peptide Autologous Dendritic Cell Vaccination in Previously Vaccinated Men on NCI 09-C-01392015-05-122022-03-252022-08-17
Carfilzomib, Lenalidomide, and Dexamethasone for Smoldering Multiple Myeloma2012-05-292022-03-032022-07-06
CT COMPARE: CT Coronary Angiography to Measure Plaque Reduction2016-04-112022-01-27
A Phase 2 Study of the MET Kinase Inhibitor INC280 in Papillary Renal Cell Cancer2014-01-242021-12-172022-12-09
Denosumab Treatment for Fibrous Dysplasia2019-06-132021-11-17
Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Melanoma2013-12-122021-10-142022-11-18
Cognitive vs. Emotional Psychopharmacological Manipulations of Fear vs. Anxiety2014-06-162021-10-072022-10-03
A Phase II Single Arm Pilot Study of the Chk1/2 Inhibitor (LY2606368) in BRCA1/2 Mutation Associated Breast or Ovarian Cancer, Triple Negative Breast Cancer, High Grade Serous Ovarian Cancer, and Metastatic Castrate-Resistant Prostate Cancer2015-01-202021-08-272022-07-14
Standard of Care Alone or in Combination With Ad-CEA Vaccine and Avelumab in People With Previously Untreated Metastatic Colorectal Cancer QUILT-2.0042017-04-052021-08-252021-11-09
Phase II Trial of Alemtuzumab (Campath) and Dose-Adjusted EPOCH-Rituximab (DA-EPOCH-R) in Relapsed or Refractory Diffuse Large B-Cell and Hodgkin Lymphomas2009-10-222021-08-062022-08-08
Etidronate for Arterial Calcifications Due to Deficiency in CD73 (ACDC)2012-08-202021-08-062022-07-13
Avelumab (Bavencio) With IL-15 in Subjects With Clear-Cell Renal Carcinoma2020-05-262021-07-232022-03-31
Prebiotics and Metformin Improve Gut and Hormones in Type 2 Diabetes in Youth (MIGHTY-fiber)2020-03-102021-07-152022-06-10
Chemotherapy Plus Vaccination to Treat Mantle Cell Lymphoma2000-06-012021-06-092022-11-02
Combining CRLX101, a Nanoparticle Camptothecin, With Enzalutamide in People With Progressive Metastatic Castration Resistant Prostate Cancer Following Prior Enzalutamide Treatment2019-03-262021-05-152022-05-02
Sunitinib for Advanced Thymus Cancer Following Earlier Treatment2012-05-152021-04-302022-04-15
Marizomib for Recurrent Low-Grade and Anaplastic Supratentorial, Infratentorial, and Spinal Cord Ependymoma2020-01-222021-04-302021-10-08
Sunitinib in Sarcomas of the Central Nervous System2019-02-212021-04-022022-02-14
Fostamatinib for Hospitalized Adults With COVID-192020-10-082021-03-302022-02-14
ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma2018-01-172021-03-182021-12-17
A Pilot Study of Combined Immune Checkpoint Inhibition in Combination With Ablative Therapies in Subjects With Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC)2016-07-052021-02-172022-02-10
M7824 in Subjects With HPV Associated Malignancies2018-02-272021-02-022021-12-27
Dexamethasone to Prevent Oral Chronic Graft-versus-Host Disease2006-11-242021-02-012022-01-20
Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Mutated or Viral Neoantigens in a Patient With Metastatic Cancer Plus the Administration of Pembrolizumab2021-01-272021-01-27